Premium
The problem of multiple lesions of the breast
Author(s) -
Hutter Robert V. P.,
Kim Dae Un
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197112)28:6<1591::aid-cncr2820280639>3.0.co;2-j
Subject(s) - medicine , autopsy , incidence (geometry) , breast cancer , pathology , cancer , general surgery , surgery , radiology , physics , optics
The concept of multicentricity of cancer of the breast is not new; however, reinvestigation of its prevalence is now necessary because of the currently wider recognition of noninfiltrating and minute cancers. A technique is described for whole organ studies correlating radiographic, subgross, and microscopic findings. Comparative studies of surgical specimens and autopsy specimens are in progress. If minimal and multicentric lesions are found to be as prevalent in autopsy specimens as in surgical specimens this would indicate either low expressivity or long latency for the development of clinical infiltrating cancers. However, if there is a significant difference in incidence of minimal lesions in autopsy specimens compared with surgical specimens, this finding would provide great incentive to develop screening programs to find and treat patients with these early lesions.