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Mucoepidermoid tumors of bronchial glands
Author(s) -
Turnbull Alan D.,
Huvos Andrew G.,
Goodner John T.,
Foote Frank W.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197109)28:3<539::aid-cncr2820280302>3.0.co;2-g
Subject(s) - medicine , mucoepidermoid carcinoma , malignancy , salivary gland , pathology , natural history , lung , lung cancer , disease , cancer
Mucoepidermoid tumors of bronchial gland origin are extremely rare, and little is known about their natural history. Clinically, their behavior in salivary glands where they were first described is characterized by a low, intermediate, or high degree of malignancy which may be predicted by the histologic appearance of the tumor. The few available reports of these tumors occurring in the lung suggest that they are either clearly benign or of intermediate malignancy, characterized mainly by local invasion. A review of approximately 5,000 patients with cancer of the lung, seen at Memorial Hospital between 1949 and 1968, was undertaken and 12 patients were found whose tumors satisfied the histologic criteria for this diagnosis. This represents one thiord as many cases as have been reported to date. All were considered to be of high‐grade malignancy. The information collected suggests that these patients follow a clinical course comparable to that of high‐grade mucoepidermoid carcinomas of salivary glands. All were dead of disease regardless of treatment within 18 months of the onset of their first discernible symptom.