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Management of multiple polyposis of the large bowel
Author(s) -
Moertel Charles G.,
Hill John R.,
Adson Martin A.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197107)28:1<160::aid-cncr2820280132>3.0.co;2-q
Subject(s) - medicine , rectum , colorectal cancer , rectal polyp , colectomy , gastroenterology , carcinoma , cancer , general surgery
The course of 178 patients with multiple polyposis has been followed from the time of treatment with subtotal colectomy and ileorectosigmoidostomy. Rectal carcinoma was not observed in 35 patients who did not have rectal polyps initially. Among 143 patients whose polypoid disease involved the rectum, 31 had rectal cancer at the time of this report. The occurrence rate increased from 5% in patients followed for 5 years to 59% in those followed for 23 years, despite frequent proctosigmoidoscopic surveillance. The tendency to rectal carcinoma was enhanced in the female patient, the patient with carcinoma in the resected colon, and the patient with more numerous rectal polyps at initial diagnosis. Colectomy with ileorectosigmoidostomy is inadequate treatment for multiple polyposis of the large bowel diffusely involving both colon and rectum.