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Hemangioma, hemangiopericytoma, and hemangioendothelioma (angiosarcoma) of bone
Author(s) -
Unni Krishnan K.,
Ivins John C.,
Beabout John W.,
Dahlin David C.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197106)27:6<1403::aid-cncr2820270621>3.0.co;2-6
Subject(s) - medicine , angiosarcoma , hemangiopericytoma , hemangioendothelioma , anaplasia , hemangiosarcoma , hemangioma , radiation therapy , osteolysis , radiology , surgery , pathology
Sixty‐nine cases of bone tumors of vascular origin, excluding cases of lymphangiomas and massive osteolysis, were found in a complete review of the surgical files of the Mayo Clinic. There were 56 hemangiomas, and these often produced roentgenologic diagnostic problems. Most were easily managed surgically, although some vertebral hemangiomas required radiation therapy. There were known multicentric lesions in only 2 of the 56 cases. Hemangiopericytomas accounted for 4 of the 69 cases. In these 4, the clinical courses were characteristically unpredictable. There were 9 hemangioendotheliomas. These 9 were added to 13 cases in which specimens were submitted for review. In 6 of the 22 cases, there was multifocal involvement. In this group of 22 cases, it was impractical to differentiate a separate group and designate it as angiosarcoma. Half of the 22 patients died, 1 of known unrelated disease. Surgical extirpation, when possible, and irradiation of lesions incompletely excised or surgically inaccessible seem logical principles in treatment. In these cases of hemangioendotheliomas, the most important indicator of prognosis was the grade of anaplasia.