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Integrated irradiation and surgery in the treatment of apical lung cancer
Author(s) -
Hilaris Basil S.,
Luomanen Raymond K.,
Beattie Edward J.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197106)27:6<1369::aid-cncr2820270615>3.0.co;2-b
Subject(s) - medicine , surgery , thoracotomy , lung cancer , survival rate , radiation therapy , 5 year survival rate , lung , resection , oncology
From 1938 through 1968, 106 patients with previously untreated apical lung cancer were seen at Memorial Hospital. Eleven patients have survived for 5 years or more, a 5‐year survival rate of almost 10%. Of 13 additional patients seen during the same period after definitive treatment elsewhere, none have survived for 5 years. Preoperative irradiation followed by complete resection of the tumor is the most beneficial procedure and worthy of further trial. However, only 9% of the explored patients had a complete resection at Memorial Hospital. Interstitial implants at thoracotomy are most valuable for those patients with unresectable lesions resulting in a 5‐7ear survival rate of 16%. The combination of resection of the parenchymal cancer and implantation of the chest wall residual disease yielded a 5‐year survival rate of about 30%. Finally, external radiation therapy for patients with inoperable apical lung cancer resulted in a 5‐year survival rate of 5%.