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Gastric polyps. Histologic types and their relationship to gastric carcinoma
Author(s) -
Tomasulo Joseph
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197106)27:6<1346::aid-cncr2820270612>3.0.co;2-v
Subject(s) - medicine , hyperplastic polyp , gastric polyp , adenomatous polyps , gastroenterology , stomach , carcinoma , pathology , atypia , cancer , colonoscopy , colorectal cancer
In a study of the relationship between gastric polyps and carcinoma, a series of 97 cases of gastric polyps were studied histologically and follow‐up information obtained. Thirty‐five per cent of the total series of gastric polyps were found as incidental findings in stomachs with gastric carcinoma. Polyps were subdivided by gross appearance into single polyps, multiple discrete polyps, or gastric polyposis; no significant difference in association with carcinoma was found for these gross types. Polyps could be subdivided microscopically into hyperplastic and adenomatous types. Hyperplastic polyps were relatively more common (76%), and were randomly distributed in the stomach. Adenomatous polyps were usually antral in location and were histologically similar to the adenomatous polyps of the colon. Marked epithelial atypia (in‐situ carcinoma) was seen only in polyps of the adenomatous type. Adenomatous polyps were associated with carcinoma more frequently than hyperplastic polyps—59% and 28%, respectively. Follow‐up information on a total of 40 patients who underwent surgery for gastric polyps without associated carcinoma showed that 3 developed subsequent polyps and only one developed a polypoid carcinoma. The initial polyps in these cases were multiple, greater than 2 cm in size, and, in each case, at least one was of the adenomatous type. The subdivision of polyps into 2 histologic types revealed the close morphological and statistical relationship of the adenomatous type of gastric polyp to gastric carcinoma. This relationship is otherwise obscured by the presence of the more numerous hyperplastic polyps. In almost all circumstances, simple polypectomy with a rim of uninvolved adjacent mucosa is sufficient treatment.