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Genetic factor in malignant melanoma
Author(s) -
Wallace D. C.,
Exton Lesley A.,
McLeod G. R. C.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197105)27:5<1262::aid-cncr2820270534>3.0.co;2-6
Subject(s) - medicine , heritability , melanoma , dermatology , genetics , cancer research , biology
A study of 113 family histories from a total of 125 consecutive cases of malignant melanoma from Brisbane and surrounding areas, covering 923 first degree relatives, has shown a heritability of liability to this condition of approximately 11%. Evidence was found to suggest that the hereditary factor is polygenic in nature.