Premium
Severe pain in gynecologic cancer. Trial of pentazocine, morphine, and a placebo
Author(s) -
Frankendal Bo,
Kjellgren Olle
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197104)27:4<842::aid-cncr2820270414>3.0.co;2-p
Subject(s) - pentazocine , medicine , analgesic , placebo , morphine , anesthesia , cancer pain , gynecologic cancer , randomized controlled trial , cancer , surgery , ovarian cancer , alternative medicine , pathology
The analgesic efficacy of pentazocine has been tested in severe pain due to gynecologic cancer. A comparative trial was conducted between 60 mg pentazocine, 10 mg morphine, and 10 mg placebo in 35 patients. The drugs were administered in a randomized order by the double‐blind technique. Intensity and relief of pain were classified by scores. The analgesic efficacy was analyzed in 5 different ways. No significant difference in analgesic efficacy was observed between morphine and pentazocine. Both drugs have a significantly better analgesic efficacy than placebo.