Premium
Effect of irradiation on the maturation of Wilms' tumor
Author(s) -
Bannayan George A.,
Huvos Andrew G.,
D'Angio Giulio J.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197104)27:4<812::aid-cncr2820270409>3.0.co;2-e
Subject(s) - wilms' tumor , medicine , wilms tumour , pathology , irradiation , primary (astronomy) , cancer research , physics , nuclear physics , astronomy
A study was undertaken to ascertain the morphological differences that exist between the primary tumor and the metastatic deposits of 55 selected cases of Wilms' tumors. The observations in this study point towards a greater degree of non‐epithelial differentiation and a decrease in the tubular and glomerular differentiation in the metastases as compared to the primary tumors. The study also suggests that irradiation accelerates and possibly induces non‐epithelial differentiation.