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Small cell tumors of the thyroid A clinicopathologic study
Author(s) -
Rayfield E. J.,
Nishiyama R. H.,
Sisson J. C.
Publication year - 1971
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(1971)28:4<1023::aid-cncr2820280428>3.0.co;2-h
Subject(s) - medicine , thyroid , radiation therapy , lymphoma , pathology , cyclophosphamide , reticulum cell sarcoma , lesion , cell , radiology , chemotherapy , genetics , biology
Fourteen cases of small cell tumors of the thyroid gland were seen at the University of Michigan Medical Center from 1932 to 1969. Nine were identified as reticulum cell sarcomas. Although the microscopic patterns in these were similar to those in the literature describing small cell carcinomas of the thyroid, four of seven patients who were treated with resection and radiation were apparently cured. No useful purpose was found for classifying tumors as small cell carcinomas. Two cases with lymphocytic lymphomas were also apparently cured by radiation, treatment. In three patients, the primary thyroid cancers were Burkitt's lymphomas. These went unrecognized during life and were also treated with radiation therapy; no patient survived longer than 8 months. Since cyclophosphamide may be more efficacious than radiation therapy for Burkitt's lymphoma, recognition of this lesion is of practical importance.