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Familial juvenile polyposis of the colon
Author(s) -
Haggitt Rodger C.,
Pitcock James A.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197012)26:6<1232::aid-cncr2820260609>3.0.co;2-8
Subject(s) - medicine , juvenile , familial adenomatous polyposis , gastroenterology , colorectal cancer , adenomatous polyposis coli , jejunum , carcinoma , cancer , biology , genetics
Familial juvenile polyposis of the colon is characterized by multiple juvenile polyps, frequent recurrences, and a family history of carcinoma or adenomatous polyposis of the colon. Two cases are presented, and the 6 previously reported families with this condition are summarized. A few of the lesions in these patients had features of both juvenile and adenomatous polyps, and one patient had an adenomatous polyp of the jejunum. Further studies are necessary to determine the frequency with which juvenile polyposis and carcinoma of the colon occur in the same family, and to identify a possible relationship between the 2 in these families.