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Nongonadal neoplasia in Turners syndrome
Author(s) -
Wertelecki Wladimir,
Fraumeni Joseph F.,
Mulvihill John J.,
Mulvihill John J.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197008)26:2<485::aid-cncr2820260233>3.0.co;2-3
Subject(s) - medicine , turner syndrome , turner's syndrome , phenotype , pathology , pediatrics , genetics , biology , gene
Evaluation of extragonadal tumors in Turner's syndrome by a multi‐hospital survey of 289 cases and literature review showed a preponderance of neurogenic tumors among children and young adults. These neoplasms occurred also in a small series of “male Turner's syndrome,” suggesting that developmental neural defects, hamartomatous growths, and susceptibility to neurogenic tumors are related to one another as expressions of Turner's phenotype.
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