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“Mesonephroma ovarii (hypernephroid carcinoma)”. Light microscopic and ultrastructural study of a case
Author(s) -
Okagaki Takashi,
Richart Ralph M.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197008)26:2<453::aid-cncr2820260229>3.0.co;2-w
Subject(s) - ultrastructure , pathology , basement membrane , glycogen , vacuole , endoplasmic reticulum , lumen (anatomy) , lipid droplet , carcinoma , cytoplasm , electron microscope , lamellar granule , biology , anatomy , medicine , microbiology and biotechnology , endocrinology , physics , optics
A case of “mesonephroma ovarii” of hypernephroid type (Saphir) in a 67year‐old woman was studied by light and electron microscopy. The cells contain strongly PAS‐positive material at a light microscopic level, Best's carmine positive. Mucicarmine was positive only in secretion. At an ultrastructural level, the cells were characterized by the presence of short microvilli, glycogen granules, lamellar endoplastic reticulum in layers, occasional vacuoles, scanty lipid bodies, small secretory bodies surrounded by unit membranes, and finely granular material present in the lumen. The cells have interdigitating contacts and desmosomes. A basement membrane is consistently present around tubules or acini. The neoplastic cells did not resemble those seen in endometrioid carcinoma of the ovary or renal cell carcinoma, which have been suggested by other authors as origins of the mesometanephroma. At an ultrastructural level, the neoplastic cells resembled none of the tumors previously postulated as of the same origin.