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Lymphoreticular sarcomas with primary involvement of waldeyer's ring. Clinical evaluation of 225 cases
Author(s) -
Banfi Alberto,
Bonadonna Gianni,
Carnevali Giuseppe,
Molinari Roberto,
Monfardini Silvio,
Salvini Enea
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197008)26:2<341::aid-cncr2820260216>3.0.co;2-f
Subject(s) - medicine , tonsil , gastrointestinal tract , soft tissue , primary tumor , pathology , radiology , cancer , metastasis
A total of 225 consecutive untreated patients with lymphoreticular sarcomas with primary involvement of Waldeyer's ring was evaluated (151 without lymphography and 74 with lymphography). On admission, the anatomical distribution of the primary growth within Waldeyer's ring was as follows: tonsil, 40%; nasopharynx, 27.5%; base of tongue, 2.7%; soft palate, 2.7%; oropharynx, 0.9%; other sites, 26.2%. In the group studied without lymphography, the disease was confined to Waldeyer's ring in 22.5% of cases and had spread to the cervical nodes in 62.3% and to distant nodes in 15.2%. In the group studied more recently with lymphography, these figures were 13.5%, 41.9%, and 44.6%, respectively. At the time of initial evaluation, the lymphoma involved extranodal sites in only 24 of 225. In the 74 cases evaluated with lymphography, the mode of spread was studied by observing the first site of recurrence after radiotherapy. New manifestations occurred in most patients within 2 years from the end of treatment and preferentially in extranodal sites. The involvement of the gastointestinal tract, either at the time of admission or early in the follow‐up, was 20% in the group studied with lymphography. The possibility that a certain number of lymphoreticular sarcomas could arise concomitantly in Waldeyer's ring and in the gastrointestinal tract is discussed.