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Abnormalities of lung function in malignant lymphoma
Author(s) -
Valenca Laercio M.,
Aisenberg Alan C.,
Kazemi Homayoun
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197007)26:1<154::aid-cncr2820260121>3.0.co;2-w
Subject(s) - medicine , hypoxemia , hyperventilation , lymphoma , pathology , diffusing capacity , lung , autopsy , pulmonary function testing , biopsy , interstitial lung disease , lung function
Studies of lung function in 3 patients with symptomatic secondary pulmonary lymphoma (2 with Hodgkin's disease and one with lymphoblastic lymphoma) showed an interstitial pattern of dysfunction. The lymphomatous infiltration and associated nonspecific patchy interstitial fibrotic lesions seen at autopsy and on biopsy specimens were extensive enough to account for the decrease in lung volumes, low carbon monoxide diffusing capacity, hypoxemia, and hyperventilation.