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Papillary carcinoma of the thyroid gland. Sizes of 525 tumors found at autopsy in Hiroshima and Nagasaki
Author(s) -
Sampson Richard J.,
Key Charles R.,
Buncher C. Ralph,
Oka Hisao,
Iijima Soichi
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197006)25:6<1391::aid-cncr2820250618>3.0.co;2-y
Subject(s) - medicine , autopsy , thyroid , papillary carcinoma , thyroid tumors , carcinoma , population , thyroid carcinoma , pathology , physiology , environmental health
Five hundred twenty‐five cases of papillary carcinoma of the thyroid, diagnosed at autopsy in Hiroshima and Nagasaki, Japan, were investigated for sex differences; 274 cases were found in 1,453 females, 251 in 1,614 males. The greatest dimensions of the tumors by sex have log‐normal distributions, with mean 0.20 cm for females and 0.13 cm for males. Tumors in females were, as a population, significantly larger than tumors in males (p < .001). The data are in agreement with the presence of a growth‐promoting factor which is greater in females than in males. Tumors initiated by radiation and those initiated by other causes seem to be equally promoted by this factor.