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Serum alpha‐feto‐protein and primary cancer of the liver in man
Author(s) -
Purves L. R.,
Bersohn I.,
Geddes E. W.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197006)25:6<1261::aid-cncr2820250603>3.0.co;2-j
Subject(s) - medicine , primary cancer , cancer , immunodiffusion , bantu languages , alpha (finance) , liver cancer , alpha fetoprotein , radial immunodiffusion , pathology , fetal protein , gastroenterology , antibody , immunology , surgery , pregnancy , fetus , biology , construct validity , genetics , patient satisfaction , linguistics , philosophy , hepatocellular carcinoma
Cases with abnormal liver function tests, Bantu blood donors, neonates, Caucasian patients with primary cancer of the liver, and male Bantu mine workers with primary cancer of the liver have been investigated by means of a quantitative alpha‐feto‐protein (AFP) immunodiffusion assay. No false‐positive AFP tests have occurred, and 78% of primary liver cancer patients are positive. More sensitive tests are capable of increasing the positivity rate still further.