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Chronic malabsorption (steatorrhea, n‐ontropical sprue) in an adolescent, with death from malignant lymphoma, histiocytic type (reticulum cell sarcoma)
Author(s) -
Huntington Robert W.,
Larwood Thomas E.,
Armstrong Frank,
Palitz Shepherd,
Hance Darwood,
Moses Irving
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197001)25:1<206::aid-cncr2820250129>3.0.co;2-g
Subject(s) - medicine , malabsorption , lymphoma , sprue , malignancy , t cell lymphoma , gastroenterology , pathology , histiocyte , steatorrhea , mold , biology , genetics
The association of intestinal malabsorption with lymphoma is both more frequent and more mysterious than is generally realized. Cases of malabsorption with eventual emergence of lymphoma often are initially responsive to dietary treatment, and it may be exceedingly difficult to decide whether the malabsorption or the lymphoma comes first. These problems are illustrated by the case of an 18‐year‐old Mexican girl whose malabsorption initially responded well to dietary management. When lymphoma was first suspected, evaluation of the first biopsy material was very difficult. Although most consultants agreed that there was malignancy amid reactive hyperplasia, there was a variety of opinions as to the character of the malignancy. Later on, the pattern became clearly that of histiocytic lymphoma (reticulum cell sarcoma).