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Myelomonocytic leukemia in Hodgkin's disease
Author(s) -
Newman Donald R.,
Maldonado Jorge E.,
Harrison Edgar G.,
Kiely Joseph M.,
Linman James W.
Publication year - 1970
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(197001)25:1<128::aid-cncr2820250118>3.0.co;2-f
Subject(s) - medicine , disease , chronic myelomonocytic leukemia , polycythemia vera , polycythemia rubra vera , leukemia , metaplasia , myelofibrosis , myeloid , acute myelomonocytic leukemia , pathology , immunology , bone marrow , myelodysplastic syndromes
The records of 1,500 patients with Hodgkin's disease seen at the Mayo Clinic from 1950 to 1967 were reviewed in search of any later‐developing myelo‐proliferative disorders. No cases of polycythemia vera, agnogenic myeloid metaplasia, or primary thrombocythemia were found in patients with pre‐existent Hodgkin's disease. Three case reports of myelomonocytic leukemia (2 manifesting Auer bodies) developing 1 1/2, 5 1/2, and 18 years after the diagnosis of Hodgkin's disease are presented. Myelomonocytic leukemia does not appear to represent a transitional stage of Hodgkin's disease and is more likely related to therapy of the lymphomatous disease.