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Surgical or irradiation castration for patients with advanced breast cancer
Author(s) -
Stein Justin J.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196912)24:6<1350::aid-cncr2820240651>3.0.co;2-a
Subject(s) - medicine , castration , radiation therapy , breast cancer , surgery , abdomen , cancer , oncology , hormone
Radiation and surgical castration should be equally effective, when indicated in the treatment of breast cancer, provided that when radiation castration is done an adequate tumor dose is given and both ovaries are irradiated. Surgical castration produces an immediate effect, whereas approximately 6 weeks is required following radiation therapy to achieve the maximum ovarian effect. Exploration of the abdomen permits evaluation of this region for evidence of metastases. There is a period of hospitalization, an anesthetic and some mortality‐associated with the procedure.