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Mucous gland tumors of paranasal sinuses
Author(s) -
Rafla S.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196910)24:4<683::aid-cncr2820240405>3.0.co;2-#
Subject(s) - medicine , paranasal sinuses , radiation therapy , pathology , adenoma , radiology
Thirty‐seven cases of paranasal mucous gland tumors are presented. The natural history of these tumors is discussed, with emphasis on the relative frequency of nerve involvement (13 of 41) which is particularly common in ethmoidal and sphenoidal tumors. Most of the patients who died with disease had active local tumors (14 of 15 cases). Results of treatment are shown—the 5‐ and 10‐year survival rates free of disease were 21% (6 of 28) and 0% (none of 12) respectively. Factors which may aftect the results of treatment of these tumors are discussed; the site of origin is important, with the best results reported in tumors of the nasal fossa. A combined approach by surgery and radiotherapy yields die best results with a 5‐year survival rate of 33% (5 of 15). Apart from pleomorphic adenoma, there is no significant difference between the results of treatment of various histologic types. Paranasal mucous gland tumors are moderately radiosensitive with 8 of 22 tumors disappearing completely under treatment and another 4 showing very good regression. Cylindromas and adenocarcinomas appear to be the most radiosensitive tumors. The technique and dosage of radiotherapy are illustrated.