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Chromosome and transplantation results of a human leukocyte cell line derived from a healthy individual
Author(s) -
Christofinis G. J.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196909)24:3<649::aid-cncr2820240334>3.0.co;2-m
Subject(s) - cheek pouch , medicine , peripheral blood , chromosome , hamster , transplantation , life expectancy , ploidy , cell culture , pathology , physiology , immunology , andrology , genetics , biology , population , environmental health , gene
A leukocyte cell line designated R.P.M.I.‐1196, derived from the peripheral blood of a healthy female individual, has been cultivated for over 20 months, and the indications are that it has an indefinite life expectancy. During the period of investigation, the cells maintained a high degree of diploidy, and they were not neoplastic, as tested by the implantation into hamster cheek pouch method.