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Malignant interstitial cell tumor of the testis
Author(s) -
Tamoney Harry J.,
Noriega Alfredo
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196909)24:3<547::aid-cncr2820240318>3.0.co;2-l
Subject(s) - medicine , gynecomastia , radiation therapy , retroperitoneal lymph node dissection , cancer , dissection (medical) , endocrine system , hormonal therapy , pathology , oncology , hormone , prostate cancer , testicular cancer , surgery
A case of malignant interstitial cell tumor of the testis in man and a review of the literature is presented. This is a rare steroid‐producing tumor; a careful search revealed only 9 published cases. The inadequacy of radiotherapy in management of the disease is dramatically demonstrated. (Periaortic nodes containing metastatic cancer were identified in retroperitoneal areas previously exposed to intensive cobalt therapy.) This lack of radiosensitivity leads to a plea for the use of a radical surgical attack as initial therapy. Illustrations of the comfortable and extensive exposure for a retroperitoneal node dissection using the Nagamatsu approach and technique are presented. Particular interest is aroused by this tumor because its endocrine activity so closely resembles that of cancer of the adrenal cortex. The hormonal disturbances such as gynecomastia and elevated testosterone levels are discussed, as well as the use of OP 1 ‐DDD as a chemotherapeutic agent.