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Cutaneous lymphoid hyperplasia
Author(s) -
Caro William A.,
Helwig Elson B.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196909)24:3<487::aid-cncr2820240310>3.0.co;2-7
Subject(s) - pathology , medicine , lymphoid hyperplasia , hyperplasia , lymphoma , pseudolymphoma , lymphatic system , follicular hyperplasia , stromal cell , malignant lymphoma
Observations on 193 patients with 225 biopsied lesions showing heavy lymphoid infiltrates in the skin are presented. Lesions of cutaneous lymphoid hyperplasia are compared with those of cutaneous malignant lymphoma, and histopathologic criteria for their separation are discussed. The benign lesions could usually be separated from the malignant ones by a higher incidence of epidermal, stromal, and vascular abnormalities and by the presence of a polymorphous cellular infiltrate of well‐differentiated cells. Lesions of cutaneous lymphoid hyperplasia fall into lymphoreticular, granulomatous, and follicular histopathologic patterns, depending on the nature of the infiltrate. The malignant potential of cutaneous lymphoid hyperplasia is low, but rare examples of the association of the malignant with the benign have been recorded.