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Spermatocytic seminoma. I. Clinicopathologic study of six cases and review of the literature
Author(s) -
Rosai Juan,
Silber Igal,
Khodadolst Kavous
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196907)24:1<92::aid-cncr2820240113>3.0.co;2-e
Subject(s) - seminoma , medicine , orchiectomy , testicle , neoplasm , pathology , radiology , chemotherapy
Six cases of spermatocytic seminoma are reported, and the literature on the subject is reviewed. This neoplasm occurs in elderly persons, is grossly characterized by a gelatinous appearance, and has distinctive microscopic characteristics. Its degree of differentiation is far greater than that exhibited by classical seminoma, a tumor from which it should be separated. It is exclusively limited to the testicle and is never associated with teratomatous elements. Claims that it has a less favorable prognosis than classical seminoma are refuted; instead it is shown that the reverse is probably true. The large majority of patients have been cured by orchiectomy, whether or not postoperative irradiation therapy had been administered.