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Radiation therapy in carcinoma of the female urethra
Author(s) -
Antoniades John
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196907)24:1<70::aid-cncr2820240109>3.0.co;2-5
Subject(s) - medicine , urethra , radiation therapy , carcinoma , surgery , meatus , urology , radiology
In the interval from 1934 to 1966, 41 patients with the diagnosis of carcinoma of the female urethra were seen in the Ontario Cancer Institute. The data on 31 patients are sufficiently complete to report, with 25 patients being treated definitively and 6 palliatively. Carcinomas of the meatus are best treated by interstitial gamma ray therapy in dosages between 5500 to 6000 rads. Surgical excisions or figuration of meatal lesions should be followed by definitive local interstitial radiotherapy when there is a question of residual disease. Involvement of the distal half of die urethra without extraurethral spread can be handled in a similar fashion. Tumors of the proximal urethra or entire urethra carry a serious prognosis and should be treated by both external radiation as well as interstitial radium techniques. Treatment (surgical or radiation) to the regional lymph nodes should be reserved for demonstrated disease either on clinical examination or by lymphangiography.