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Anaplastic thyroid cancer twelve years after radioiodine therapy
Author(s) -
Baker Harvey W.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196904)23:4<885::aid-cncr2820230425>3.0.co;2-r
Subject(s) - medicine , thyroid , thyroid cancer , anaplastic thyroid cancer , radioiodine therapy , incidence (geometry) , goiter , cancer , radiation therapy , physics , optics
A patient received 2 doses of radioiodine for a diffuse toxic goiter in 1956. Twelve years later at the age of 64 she was operated on for an anaplastic cancer arising in the right lobe of the thyroid. Other thyroid neoplasms following the therapeutic use of radioiodine have also been reported although the incidence may still be within the range of statistical coincidence. There is a definite risk of later malignant change after external radiation to the thyroid in infants and children. The risk in adults seems to be smaller, and the latent period is longer. The experimental and clinical evidence indicate some caution in the therapeutic use of radioiodine.