Premium
Eccrine acrospiroma: A clinicopathologic study
Author(s) -
Johnson Bernett L.,
Helwig Elson B.
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196903)23:3<641::aid-cncr2820230318>3.0.co;2-b
Subject(s) - medicine , pathology , sweat gland , eccrine sweat gland , serous fluid , eccrine sweat , differential diagnosis , sweat , basal cell
Three hundred and nineteen examples of a histologically distinctive sweat gland tumor, the acrospiroma, are presented. The tumor occurs as a single mass in the skin and is nodular and solid or cystic. The color varies from that of the surrounding skin to red or reddish blue, and the covering skin may be smooth or thickened and verrucous. The tumors are rarely painful, and a serous or hemorrhagic fluid may drain spontaneously from them. They may recur but rarely undergo malignant change. Clinically, the tumors lack diagnostic specificity, but they should be included in the differential diagnosis of nodular and cystic lesions of the skin. Histologically, the acrospiroma is readily differentiated from other sweat gland tumors, but frequently it is confused with lesions of a metastatic renal cell carcinoma and sometimes with lesions of squamous cell carcinoma. On the basis of histologic and histochemical studies, we believe that the cells of this tumor mimic those of the eccrine sweat duct and have designated the entity as eccrine acrospiroma.