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Pleomorphic lymphoma and gastric adenocarcinoma (collision neoplasm) associated with monoclonal macroglobulinemia and amyloidosis: A case report
Author(s) -
Coppola Antonio,
Yermakov Valentin,
Caggiano Vincent
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196903)23:3<576::aid-cncr2820230308>3.0.co;2-y
Subject(s) - medicine , macroglobulinemia , pathology , adenocarcinoma , stomach , lymphoma , autopsy , amyloidosis , pancreas , cancer , bone marrow , waldenstrom macroglobulinemia , monoclonal , lymphoplasmacytic lymphoma , monoclonal antibody , multiple myeloma , immunology , antibody
An unusual instance of lymphosarcoma involving the perigastric lymphnodes and presumably the stomach, associated with monoclonal IgM (Waldenstrom's macroglobulinemia) is described. At autopsy, a pleomorphic malignant lymphoma and a coexistent mucin‐secreting gastric adenocarcinoma were discovered. Cancer‐to‐cancer metastases were found in the lymph nodes, the liver, the lungs, the kidneys, the pancreas and the bone marrow. Amyloidosis of the stomach and the lung was also found. This represents the first reported case of pleomorphic lymphoma and gastric adenocarcinoma with dual metastases (collision neoplasm), associated with monoclonal macroglobulinemia and amyloidosis.