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Elastofibroma. Report of a case with special histochemical and electron‐microscopic studies
Author(s) -
Winkelmann R. K.,
Sams W. Mitchell
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196902)23:2<406::aid-cncr2820230215>3.0.co;2-m
Subject(s) - matrix (chemical analysis) , homogeneous , electron microscope , pathology , composite material , materials science , anatomy , medicine , physics , optics , thermodynamics
In elastofibroma, electron‐microscopic and histochemical techniques demonstrated that four components may be found in such tissue: elastinophilic granular aggregates, reticulin fibers, a homogeneous matrix, and, on occasion, normal elastic fibers. Lipid was observed in the elastinophilic material, and polysaccharide was found in the matrix. The material is found in and around the few fibroblasts and elastic fibers, as well as dispersed throughout the fibrous mass. It is proposed that this is a true elastodysplasia arising from the increased production of elastic matrix material.