Premium
The long‐term results of autologous transplantation of basal cell carcinoma in skin grafts
Author(s) -
Blackwell John B.,
McComb Harold
Publication year - 1969
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196901)23:1<101::aid-cncr2820230111>3.0.co;2-s
Subject(s) - medicine , basal cell carcinoma , transplantation , basal cell , basal (medicine) , carcinoma , pathology , necrosis , skin grafting , cell , surgery , biology , insulin , genetics
Autografting of basal cell carcinomas in a patient with the nevoid basal cell carcinoma syndrome resulted in early necrosis of the basal cell tumors while the remainder of the grafted skin survived and grew normally. The findings in these grafts 12 months or longer after transplantation are reported in this paper. Naked‐eye examination of ten grafts containing basal cell carcinoma revealed only two small recurrences over the period of the experiment; microscopic examination disclosed tumor foci in eight grafts. Despite this it appeared that the grafting had exercised a modifying and restrictive influence on tumor recurrence, especially in those grafts applied to a subcutaneous tissue bed. The principles of this technique to produce long‐term control of multiple basal cell carcinomas are discussed and its therapeutic value assessed.