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Ultrastructure of a hemangiopericytoma and a glomus tumor
Author(s) -
Murad Tariq M.,
Haam Emmerich Von,
Narasimha M. S. Murthy
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196811)22:6<1239::aid-cncr2820220622>3.0.co;2-2
Subject(s) - hemangiopericytoma , ultrastructure , pathology , cytoplasm , epithelioid cell , glomus tumor , glomus cell , anatomy , cell type , smooth muscle , basement membrane , medicine , biology , cell , microbiology and biotechnology , immunohistochemistry , receptor , genetics , chemoreceptor
A comparative ultrastructural study of a case of hemangiopericytoma and one of glomus tumor is presented. The study revealed the hemangiopericytoma cells to be large with large irregular nuclei. The intercellular spaces are filled with light osmiophilic material resembling basement membrane. In the glomus tumor, two types of cells are identified. The more frequent cells are epithelioid smooth muscle cells with large ovoid nuclei and cytoplasm filled with fine filaments. The second type of cell is less frequent and is recognized as a mast cell. It is suggested that the release of mast cell granules plays an important role in the contraction of epithelioid smooth muscle and therefore controls the flow of blood in the glomus structure.