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Thymoma and cancer
Author(s) -
Souadjian Jacques V.,
Silverstein Murray N.,
Titus Jack L.
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196811)22:6<1221::aid-cncr2820220619>3.0.co;2-7
Subject(s) - thymoma , medicine , myasthenia gravis , pure red cell aplasia , malignancy , cancer , pathology , neoplasm , lesion , bone marrow
Twenty‐one per cent (31 of 146) of patients who had thymoma and whose condition was followed for 20 years had a malignant lesion of a nonthymic tissue. In contrast, 8% (15 of 177) of patients who had a parathyroid adenoma had a malignant neoplasm of another tissue. A review of 1030 reported cases of thymoma showed that nonthymic malignant lesions had developed in 20% (7 of 35) of patients whose condition was followed for 5 years or more. The present study suggests that nonthymic malignancy with thymoma should be added to the list of conditions (myasthenia gravis, pure red cell aplasia, and immunoglobulin abnormalities) that generally is accepted in association with thymoma.