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The ultrastructure of fibrocystic disease of the breast
Author(s) -
Murad Tariq M.,
von Haam Emmerich
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196809)22:3<587::aid-cncr2820220315>3.0.co;2-2
Subject(s) - myoepithelial cell , fibrocystic breast disease , apocrine , fibrocystic disease , pathology , medicine , epithelium , hyperplasia , cyst , stroma , immunohistochemistry , breast cancer , cancer
Twenty‐two cases of fibrocystic disease were studied with light and electron microscopes. Histologically, the manifestations of fibrocystic disease are divided into five groups presenting a consistent light‐ and electron‐microscopic appearance that includes: blunt duct adenosis, epithelial cell hyperplasia, sclerosing adenosis, “myoepithelial cell proliferation,” cyst with atrophic epithelium and cyst with apocrine changes. Fibrous stroma, lymphocytic infiltration and other features found with fibrocystic disease are not described here because of their presence in conditions other than fibrocystic disease. On the basis of the present study it is concluded that fibrocystic disease involves both epithelial and myoepithelial cells of the mammary duct.