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Coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis. Associated with extreme elevations of blood histamine levels and maturity onset asthma
Author(s) -
Shohet Stephen B.,
Blum Stuart F.
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196807)22:1<173::aid-cncr2820220121>3.0.co;2-f
Subject(s) - medicine , chronic myelogenous leukemia , basophilic , asthma , leukemia , immunology , pathology , gastroenterology
A case of coincident basophilic chronic myelogenous leukemia and pulmonary tuberculosis is reported. Marked elevations in serum histamine levels were associated with maturity onset‐bronchial asthma which was controlled with antihistamine medication. The diagnosis of tuberculosis was established by pleural fluid cultures. The diagnosis of chronic myelogenous leukemia was established by determination of leukocyte alkaline phosphatase levels and chromosome studies. The importance of such studies in cases of tuberculosis with leukemoid reactions is stressed.