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Embryonal rhabdomyosarcoma An ultrastructural study
Author(s) -
Toker Cyril
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196806)21:6<1164::aid-cncr2820210618>3.0.co;2-r
Subject(s) - ultrastructure , embryonal rhabdomyosarcoma , cytoplasm , rhabdomyosarcoma , pathology , organelle , neoplasm , electron microscope , biology , anatomy , medicine , microbiology and biotechnology , sarcoma , physics , optics
Ultrastructural analysis of an embryonal rhabdomyosarcoma has revealed immature rhabdomyoblasts with an abundance of cytoplasmic organelles and membranous systems. More mature elements demonstrated progressive accumulation of cytoplasmic fibers which ultimately occupied the greater part of the cytoplasmic substance. Even within the largest cells encountered, however, the definitive banding of striated muscle was not observed. Characterization of the neoplasm as myosarcomatous was not possible on the basis solely of ultrastructural morphology. It is felt that the electron microscope will offer scant prospect of success in the differentiation from one another of anaplastic soft part sarcomas which have escaped definitive identification by conventional methods.