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Aspects of behavior and natural history of malignant melanoma in uganda
Author(s) -
Lewis M. G.,
Kiryabwire J. W. M.
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196805)21:5<876::aid-cncr2820210511>3.0.co;2-7
Subject(s) - natural history , medicine , melanoma , grading (engineering) , pathology , dermatology , biology , cancer research , ecology
This study indicates that generalizations about the apparent benign behavior of malignant melanoma in Africa are misleading since the majority of cases seen in Uganda have a typically rapid malignant course. The differences in natural history allow three groups to be presented. The factors of sex, age, site, size of tumor and histologic grading of cells and degree of pigmentation do not seem to be responsible for these differences and have no particular prognostic significance. This suggests a difference in host response to the presence of the tumor.