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Preoperative irradiation of osteogenic sarcoma with intra‐arterially injected yttrium‐90 microspheres: Case report
Author(s) -
Simon Norman,
Siffert Robert,
Baron Murray G.,
Mitty Harold A.,
Rudavsky Amiel
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196803)21:3<453::aid-cncr2820210315>3.0.co;2-w
Subject(s) - medicine , sarcoma , nuclear medicine , irradiation , microsphere , femur , yttrium , radiology , pathology , surgery , materials science , physics , chemical engineering , nuclear physics , engineering , metallurgy , oxide
Plastic microspheres containing yttrium‐90 were injected intra‐arterially into an osteogenic sarcoma of the femur to administer preoperative irradiation. Brems‐strahlung scans showed radioactivity localized in tumor and lungs. Specimens from the sarcoma and adjacent normal tissue were assayed for radioactivity and dose administered, about 2800 rads to the tumor and 100 rads to the adjacent skin. This method of preoperative irradiation merits further investigation.