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Medullary fibrosarcoma of bone
Author(s) -
Cunningham Myles P.,
Arlen Myron
Publication year - 1968
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196801)21:1<31::aid-cncr2820210107>3.0.co;2-8
Subject(s) - medullary cavity , medicine , fibrosarcoma , appendicular skeleton , amputation , skeleton (computer programming) , bone tumours , pathology , presentation (obstetrics) , anatomy , surgery
Twenty‐seven cases of medullary fibrosarcoma of the bone are reviewed in detail. They span a broad age range with a median age in the 40's, show a mild sex preference for men, tend to be clustered towards the end of long bones but may be found almost anywhere in the axial and appendicular skeleton. They are similar to soft tissue fibrosarcomas in their clinical presentation but are more lethal, having a 5‐year survival of 29.6%. The most significant factor relating to survival is the degree of histologic differentiation, low‐grade tumors having a favorable prognosis and anaplastic lesions an extremely poor one. Appropriate amputation is the treatment of choice.