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Stromal reaction around tumor and metastasis and prognosis after curative gastrectomy for carcinoma of the stomach
Author(s) -
Inokuchi Kiyoshi,
Inutsuka Sadamitsu,
Furusawa Motonosuke,
Soejima Kazuhiko,
Ikeda Toshihiko
Publication year - 1967
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196711)20:11<1924::aid-cncr2820201120>3.0.co;2-b
Subject(s) - medicine , stromal cell , stomach , gastrectomy , metastasis , carcinoma , gastric carcinoma , survival rate , stromal tumor , pathology , gastroenterology , oncology , cancer
The prognosis of 270 cases with carcinoma of the stomach after curative gastrectomy was studied by histologic examination of the resected specimen. In cases without metastases, when there were both fibrous and cellular stromal reaction in the main tumor, the 5‐year survival rate was 100% and, when the reaction was negative, the prognosis was 30%. If, however, there was no stromal reaction in the metastases, the prognosis was as miserable as 7.0%, with or without reaction in the main tumor. The authors conclude that stromal reaction around the carcinoma dominates the prognosis and that the prognosis can be estimated with further accuracy after analysis of the reaction in metastatic nodes.