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Acinic cell carcinoma of the parotid gland
Author(s) -
Eneroth CarlMagnus,
Jakobsson Per Å.,
Blanck Carl
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196612)19:12<1761::aid-cncr2820191202>3.0.co;2-#
Subject(s) - acinic cell carcinoma , medicine , neck dissection , parotid gland , adenoid cystic carcinoma , pathology , parotidectomy , adenolymphoma , carcinoma , incidence (geometry) , metastasis , adenoid , salivary gland , cancer , mucoepidermoid carcinoma , physics , optics
In a histological re‐examination and re‐classification of a series of 1,678 tumors of the parotid gland 37 (2.2%) exhibited the structures characteristic of acinic cell carcinoma. A long‐term follow‐up study showed that the prognosis quoad vitam in this type of tumor is poorer than previously has been inferred from short‐term follow‐ups. Thus the determinate survival rate fell from 89% at 5‐year follow‐up to 56% after 20‐year follow‐up. The prognosis is nevertheless much better than in adenoid cystic carcinoma of the parotid gland, as disclosed by a comparative study. This difference is evident after 5‐year follow‐up and becomes still more marked with time. Acinic cell carcinoma cannot be divided into a benign and a malignant variant on the basis of various histological criteria, such as infiltrative growth and high incidence of mitesis. This is because even the histologically apparently benign variant may have a clinically malignant course. Metastasis was observed in 7 cases, in 4 of them to regional lymph nodes. Since acinic cell carcinoma has proved to be a malignant, metastatic type of tumor, the authors recommend that parotidectomy be combined with neck dissection.