Premium
Meningeal relations of primary brain tumors: A histological study
Author(s) -
Eneström Sverker
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196608)19:8<1117::aid-cncr2820190811>3.0.co;2-8
Subject(s) - subarachnoid space , meninges , glioma , cerebrospinal fluid , pathology , medicine , biopsy , brain tumor , cancer research
Biopsy specimens from rapidly progressive malignant gliomas with meningeal involvement studied for (1) exfoliated tumor cells in the subarachnoid space outside the gliomatosis, (2) the invasive glioma structure in the meninges and (3) the tumor‐meningeal reaction. Desmoplastic changes in the glioma structure and distinct mesenchymal proliferation effectively shared in sealing off the subarachnoid space; no isolated tumor cells were detectable in the neighboring subarachnoid space. This seems to correlate well with the low yields of exfoliated glioma cells in the cerebrospinal fluid from meningeal gliomatosis.