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Is there A malignant freckle?
Author(s) -
Ollstein Ronald N.,
Kaplan Harold S.,
Crikelair George F.,
Lattes Raffaele
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196606)19:6<767::aid-cncr2820190605>3.0.co;2-k
Subject(s) - medicine , histopathology , lesion , dermatology , melanoma , pathology , cancer research
The malignant freckle diagnosis is best suited to the clinical pattern of an indolent facial pigmented lesion of the elderly. The histopathology of such tumors is variable and not diagnostic. The use of the histopathologic diagnosis of malignant freckle is not advised, especially in extrafacial lesions, where its unjustifiable implied good prognosis is misleading. These conclusions are based on a review of 23 cases of so‐called malignant freckle diagnosed pathologically at Presbyterian Hospital. Of the 18 extrafacial lesions studied 17 proved on “second look” to be invasive malignant melanoma. The 5 facial lesions, despite their clinical similarities, demonstrated variable pathology.