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Observations on a heifer with cutaneous lymphosarcoma
Author(s) -
Marshak Robert R.,
Hare W. C. D.,
Dutcher Ray M.,
Schwartzman Robert M.,
Switzer John W.,
Hubben Klaus
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196605)19:5<724::aid-cncr2820190519>3.0.co;2-r
Subject(s) - leucosis , etiology , pathogenesis , medicine , pathological , disease , skin lesion , pathology , dermatology , immunology , virus
Cutaneous lesions are exceedingly rare in cattle with lymphosarcoma in the United States. Such cases are of particular interest because of a widely held belief, on epidemiologic grounds, that the etiology and pathogenesis of “skin leucosis” differs from the more typical adult form of the disease. Except for cutaneous lesions, a 20‐month‐old grade Holstein heifer originating on a Pennsylvania farm showed the clinical configuration, pathological alterations and laboratory findings commonly observed in cattle with generalized lymphosarcoma. It is, therefore, difficult to accept the view that the etiology and pathogenesis of lymphosarcoma in this animal with skin manifestations (one of many possible expressions of the disease) was fundamentally different from other forms of lymphosarcoma.