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Ultrastructure of benign peripheral nerve sheath tumors
Author(s) -
Waggener John D.
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196605)19:5<699::aid-cncr2820190516>3.0.co;2-h
Subject(s) - neurofibroma , ultrastructure , pathology , neuroma , medicine , organelle , anatomy , schwann cell , tumor cells , cytoplasm , biology , microbiology and biotechnology , neurofibromatosis , cancer research , surgery
The ultrastructure of the neurilemmoma has been compared with that of the neurofibroma. Large aggregates of extremely thin cytoplasmic processes characterize Antoni type A neurilemmoma tissue. In Antoni type B tissue, the tumor cells present as globular structures containing many organelles and osmophilic material. The neurofibroma consists of widely scattered cells which closely resemble non‐neoplastic Schwann cells. Although the patterns of the 2 tumors are widely different, morphological evidence is presented which supports the concept that both of the lesions arise from Schwann cells. Some features of a human traumatic neuroma are presented.

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