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Clinical study of forty‐nine patients with malignant melanoma
Author(s) -
Lehman James A.,
Cross Frederick S.,
Richey Dewayne G.
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196605)19:5<611::aid-cncr2820190503>3.0.co;2-m
Subject(s) - medicine , melanoma , trunk , dissection (medical) , lesion , lymph node , surgery , lymph , radiology , pathology , cancer research , ecology , biology
A study of 49 patients with malignant melanoma of the skin occurring over an 18‐year period is presented. The over‐all 5‐year survival was 43%. The prognosis was uniformly better for females and for lesions less than one cm. A poor prognosis was associated with primary lesions on the trunk, ulceration or hemorrhage of the primary and clinically and microscopically positive nodes. The authors conclude that a wide local excision of the primary lesion, including a 3 to 5 cm margin of skin, combined with an in‐continuity regional lymph node dissection should be the treatment of choice.