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Observations on cortical nodules in human adrenal glands. Their relationship to neoplasia
Author(s) -
Cohen Richard B.
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196604)19:4<552::aid-cncr2820190414>3.0.co;2-l
Subject(s) - adrenal cortex , medicine , hyperplasia , adenoma , pathology , cortex (anatomy) , neuroscience , biology
Observations are reported on the characteristics of adrenocortical nodules in human adrenals in several circumstances. It is shown that they may differ biochemically from the surrounding cortex and from each other and that on occasion may have some structural and functional characteristics considered to be typical of adenomas. The occurrence of hyperplasia and adenoma sequentially in the same patients as a cause of Cushing's disease also is noted. The possible relationships of hyperplasia and benign neoplasia in the adrenal cortex is discussed.