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Lung as a transplant site for malignant tumors in rodents
Author(s) -
Epstein Samuel S.
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196603)19:3<454::aid-cncr2820190321>3.0.co;2-x
Subject(s) - medicine , lung , pathology , lung tumor , chemotherapy , incidence (geometry) , lung cancer , bronchogenic carcinoma , surgery , physics , optics
Rodent lungs have been inoculated with tumor cell suspensions from various sources by a previously described “intra‐oral” technique. The technique is simple and rapid and has yielded a high incidence of bronchogenic and alveogenic pulmonary tumors. The reproducibility of this technique would allow its use in providing a model for evaluating the effects of chemotherapy on malignant neoplasms of the air passages of the lung.