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Natural history of Hodgkin's disease as related to staging
Author(s) -
Peters M. Vera,
Alison Ruth E.,
Bush Raymond S.
Publication year - 1966
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(196603)19:3<308::aid-cncr2820190303>3.0.co;2-p
Subject(s) - natural history , medicine , disease , radiation therapy , epidemiology , incidence (geometry) , cancer , pediatrics , surgery , pathology , physics , optics
Since the natural history of untreated Hodgkin's disease cannot be determined by the few case reports in the literature, a study has been made based on the wider experience recorded in the case histories of the patients registered in a large radiotherapy center. An analysis of 323 successive patients treated at the Ontario Cancer Institute, Toronto, who have been followed more than 10 years has revealed at least 2 different patterns in the course of Hodgkin's disease—one potentially curable, the other not yet fully understood. These 2 forms usually can be identified at the time of diagnosis. When this is possible more adequate radiotherapy can be prescribed. The finding of 2 separate clinical courses fits in with the epidemiological concept of 2 different populations in Hodgkin's disease which have been identified by studies in age incidence.