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A study on the fabrication of porous chitosan/gelatin network scaffold for tissue engineering
Author(s) -
Shen F,
Cui Y L,
Yang L F,
Yao K D,
Dong X H,
Jia W Y,
Shi H D
Publication year - 2000
Publication title -
polymer international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.592
H-Index - 105
eISSN - 1097-0126
pISSN - 0959-8103
DOI - 10.1002/1097-0126(200012)49:12<1596::aid-pi553>3.0.co;2-s
Subject(s) - glutaraldehyde , gelatin , chitosan , scaffold , porosity , tissue engineering , materials science , chemical engineering , polyelectrolyte , fabrication , freeze drying , composite material , polymer chemistry , polymer , biomedical engineering , chemistry , organic chemistry , chromatography , medicine , alternative medicine , pathology , engineering
A novel porous chitosan/gelatin scaffold for tissue engineering was prepared via polyelectrolyte complex formation, freeze drying and post‐crosslinking with glutaraldehyde. The porosity and mean pore diameters could be controlled within 30∼100 µm by varying the original water content and the freezing conditions. Dipping the scaffolds in poly(lactic acid) provided good mechanical properties making it a promising candidate towards tissue engineering. © 2000 Society of Chemical Industry